CT-to-X-ray Distillation Under Tiny Paired Cohorts: An Evidence-Bounded Reproducible Pilot Study
arXiv:2603.29167v1 Announce Type: new Abstract: Chest X-ray and computed tomography (CT) provide complementary views of thoracic disease, yet most computer-aided diagnosis models are trained and deployed within a single imaging modality. The concrete question studied here is narrower and deployment-oriented: on a patient-level paired chest cohort, can CT act as training-only supervision for a binary disease versus non-disease X-ray classifier without requiring CT at inference time? We study this setting as a cross-modality teacher--student distillation problem and use JDCNet as an executable pilot scaffold rather than as a validated superior architecture. On the original patient-level paired split from a public paired chest imaging cohort, a stripped-down plain cross-modal logit-KD control
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Abstract:Chest X-ray and computed tomography (CT) provide complementary views of thoracic disease, yet most computer-aided diagnosis models are trained and deployed within a single imaging modality. The concrete question studied here is narrower and deployment-oriented: on a patient-level paired chest cohort, can CT act as training-only supervision for a binary disease versus non-disease X-ray classifier without requiring CT at inference time? We study this setting as a cross-modality teacher--student distillation problem and use JDCNet as an executable pilot scaffold rather than as a validated superior architecture. On the original patient-level paired split from a public paired chest imaging cohort, a stripped-down plain cross-modal logit-KD control attains the highest mean result on the four-image validation subset (0.875 accuracy and 0.714 macro-F1), whereas the full module-augmented JDCNet variant remains at 0.750 accuracy and 0.429 macro-F1. To test whether that ranking is a split artifact, we additionally run eight patient-level Monte Carlo resamples with same-case comparisons, stronger mechanism controls based on attention transfer and feature hints, and imbalance-sensitive analyses. Under this resampled protocol, late fusion attains the highest mean accuracy (0.885), same-modality distillation attains the highest mean macro-F1 (0.554) and balanced accuracy (0.660), the plain cross-modal control drops to 0.500 mean balanced accuracy, and neither attention transfer nor feature hints recover a robust cross-modality advantage. The contribution of this study is therefore not a validated CT-to-X-ray architecture, but a reproducible and evidence-bounded pilot protocol that makes the exact task definition, failure modes, ranking instability, and the minimum requirements for future credible CT-to-X-ray transfer claims explicit.
Subjects:
Computer Vision and Pattern Recognition (cs.CV)
Cite as: arXiv:2603.29167 [cs.CV]
(or arXiv:2603.29167v1 [cs.CV] for this version)
https://doi.org/10.48550/arXiv.2603.29167
arXiv-issued DOI via DataCite (pending registration)
Submission history
From: Bo Ma Dr [view email] [v1] Tue, 31 Mar 2026 02:25:33 UTC (673 KB)
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