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All-in-One Augmented Reality Guided Head and Neck Tumor Resection

arXiv cs.HCby [Submitted on 31 Mar 2026]April 1, 20261 min read1 views
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arXiv:2603.29495v1 Announce Type: cross Abstract: Positive margins are common in head and neck squamous cell carcinoma, yet intraoperative re-resection is often imprecise because margin locations are typically communicated verbally from pathology. We present an all-in-one augmented reality (AR) system that relocalizes positive margins from a resected specimen to the resection bed and visualizes them in situ using HoloLens 2 depth sensing and fully automated markerless surface registration. In a silicone phantom study with six medical trainees, markerless registration achieved target registration errors comparable to a marker-based baseline (median 1.8 mm vs. 1.7 mm; maximum < 4 mm). In a margin relocalization task, AR guidance reduced error from verbal guidance (median 14.2 mm) to a few mi

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Abstract:Positive margins are common in head and neck squamous cell carcinoma, yet intraoperative re-resection is often imprecise because margin locations are typically communicated verbally from pathology. We present an all-in-one augmented reality (AR) system that relocalizes positive margins from a resected specimen to the resection bed and visualizes them in situ using HoloLens 2 depth sensing and fully automated markerless surface registration. In a silicone phantom study with six medical trainees, markerless registration achieved target registration errors comparable to a marker-based baseline (median 1.8 mm vs. 1.7 mm; maximum < 4 mm). In a margin relocalization task, AR guidance reduced error from verbal guidance (median 14.2 mm) to a few millimeters (median 3.2 mm), with all AR localizations within 5 mm error. These results support the feasibility of markerless AR margin guidance for more precise intraoperative re-excision.

Subjects:

Computer Vision and Pattern Recognition (cs.CV); Emerging Technologies (cs.ET); Human-Computer Interaction (cs.HC)

Cite as: arXiv:2603.29495 [cs.CV]

(or arXiv:2603.29495v1 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2603.29495

arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Yue Yang [view email] [v1] Tue, 31 Mar 2026 09:38:52 UTC (23,158 KB)

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